Recently, there have been frequent developments in the field of chemical active pharmaceutical ingredient (API) cyazofamid, with significant progress in market supply and demand, product innovation, and regulatory aspects. As a fungicide widely used in the agricultural sector, cyazofamid continues to attract industry attention with its unique performance advantages.
The market supply and demand are stable, and prices remain stable
According to the data from the China Agricultural Lihua Technical Market Quotes 20250803, the current market quotation for cyazofamid technical is 390,000 yuan/ton, with the overall market performing stably. From the supply side, the operating rates of cyazofamid production enterprises remain relatively stable, capable of meeting the regular market demand. With the increasing global attention to agricultural product quality and food safety, there is a persistent demand for efficient and low-toxic fungicides. Cyazofamid, with its excellent control effect on diseases caused by oomycetes and clubroot, such as its outstanding performance in controlling common crop diseases like potato and tomato late blight and downy mildew, has a relatively solid market demand. According to a survey by DIResearch, the global market size of cyazofamid is expected to reach 124 million US dollars in 2025 and is projected to climb to 144 million US dollars by 2032, with a compound annual growth rate (CAGR) of 2.15% (2025-2032). This data fully demonstrates the future growth potential and positive development trend of the cyazofamid market.
Innovative products are launched to enhance prevention and control effectiveness
On the morning of February 25, 2025, the "20% pyraclostrobin-fludioxonil suspension" registered by Guangdong ZhenGe under the authorization of Syngenta was launched in Jinan, Shandong Province. This new product launch attracted widespread attention within the industry. Downy mildew has always been a key and difficult issue in plant disease control, and the launch of this product provides a new powerful weapon to address this challenge. Yang Tao, product manager of "Magnifying Glass Frost Penetration" at Guangdong ZhenGe, explained that the combination of pyraclostrobin and fludioxonil was chosen based on three major advantages: firstly, the two have completely different action sites, eliminating cross-resistance and enabling better response to resistance issues; secondly, both ingredients are highly safe and resistant to rain wash; thirdly, a large number of previous efficacy studies have shown that the combination of pyraclostrobin and fludioxonil yields the best results. Taking potato planting areas as an example, potato late blight is a rapid and widespread disease that poses great harm. Syngenta's patented compound "fludioxonil" itself has strong protective, therapeutic, spore germination inhibiting, and anti-sporulation effects, which can quickly suppress the occurrence and spread of the disease and is widely welcomed by growers. The innovative combination with pyraclostrobin further enhances the control effect against downy mildew. In experiments conducted in Chifeng, Inner Mongolia from 2023 to 2024, due to drought in 2023, the effects of using "Magnifying Glass Frost Penetration" and conventional self-protection methods were not significantly different. However, in 2024, with increased rainfall, potato late blight broke out severely. Fields using "Magnifying Glass Frost Penetration" experienced almost no late blight, forming a stark contrast with the control fields and highlighting the excellent performance of the product.
Strengthen market supervision to ensure food safety
Although cyazofamid has low oral toxicity, long-term consumption of foods with excessive cyazofamid levels can still have certain impacts on human health. Recently, market supervision departments across the country have strengthened the inspection of cyazofamid residues in foods. For example, the Market Supervision and Administration Bureau of Rui'an City found in a spot check that the fresh lychees sold by Rui'an Nenyi Fruit Store did not meet the national food safety standards for cyazofamid. The "National Food Safety Standard for Maximum Residue Limits of Pesticides in Foods" (GB 2763-2021) clearly stipulates that the maximum allowable limit of cyazofamid in fresh lychees is 0.02mg/kg, while the cyazofamid content in this batch of fresh lychees reached 0.13mg/kg. Similarly, similar situations of food non-conformity due to excessive cyazofamid levels have also occurred in Huizhou City, Dongguan City, and other places. In response to these non-conforming products, local regulatory authorities have instructed relevant units to investigate and handle them in accordance with the law, requiring the involved enterprises to immediately stop production and sales, take measures such as removing the products from shelves to control risks, and actively carry out traceability work. This series of regulatory actions aims to ensure food safety for consumers, while also urging agricultural product growers and related enterprises to strictly comply with pesticide use regulations and rationally use pesticide products such as cyazofamid.
Under the prevailing trend of green agricultural development, cyazofamid boasts a promising market prospect due to its effectiveness in disease control and relative environmental friendliness. With the continuous advancement of product innovation and the increasingly perfect market supervision, cyazofamid is expected to play a more significant role in ensuring the healthy growth of crops and enhancing the quality and safety of agricultural products.